1 of 5 | Los Angeles Rams wide receiver Puka Nacua tops my Week 6 fantasy football rankings. File Photo by Jon Soohoo/UPI | License Photo
Puka Nacua and Emeka Egbuka lead my Top-50 fantasy football wide receiver rankings for Week 6.
Amon-Ra St. Brown, Jaxson Smith-Njigba and Rome Odunze join Nacua and Egbuka in my Top 5. Ja’Marr Chase, Davante Adams, George Pickens, Deebo Samuel and A.J. Brown are among my other Top-10 options.
My top waiver-wire and free agent targets for Week 6 are available here.
All of my positional rankings will be updated until Week 6 kickoffs. Players also will be moved out of or adjusted within the rankings based on injuries. Be sure to monitor your fantasy football team lineups.
Players from the Minnesota Vikings and Houston Texans, who are on bye, should be benched or, in some cases, dropped from rosters.
Week 6 wide receiver rankings
1. Puka Nacua, Los Angeles Rams at BAL
2. Emeka Egbuka, Tampa Bay Buccaneers vs. SF
3. Amon-Ra St. Brown, Detroit Lions at KC
4. Jaxson Smith-Njigba, Seattle Seahawks at JAX
5. Rome Odunze, Chicago Bears at WAS
6. Ja’Marr Chase, Cincinnati Bengals at GB
7. Davante Adams, Los Angeles Rams at BAL
8. George Pickens, Dallas Cowboys at CAR
9. Deebo Samuel, Washington Commanders vs. CHI
10. A.J. Brown, Philadelphia Eagles at NYG
11. Jaylen Waddle, Miami Dolphins vs. LAC
12. Quentin Johnston, Los Angels Chargers at MIA
13. Drake London, Atlanta Falcons vs. BUF
14. Tetairoa McMillan, Carolina Panthers vs. DAL
15. Michael Pittman Jr., Indianapolis Colts vs. ARI
16. Xavier Worthy, Kansas City Chiefs vs. DET
17. Garrett Wilson, New York Jets vs. DEN
18. Zay Flowers, Baltimore Ravens vs. LAR
19. Chris Olave, New Orleans Saints vs. NE
20. Marvin Harrison Jr., Arizona Cardinals at IND
21. Courtland Sutton, Denver Broncos vs. NYJ
22. DK Metcalf, Pittsburgh Steelers vs. CLE
23. Jakobi Meyers, Las Vegas Raiders vs. TEN
24. Brian Thomas Jr., Jacksonville Jaguars vs. SEA
25. Terry McLaurin, Washington Commanders vs. CHI
26. Matthew Golden, Green Bay Packers vs. CIN
27. Stefon Diggs, New England Patriots at NO
28. Jauan Jennings, San Francisco 49ers at TB
29. DeVonta Smith, Philadelphia Eagles at NYG
30. Tee Higgins, Cincinnati Bengals at GB
31. Ladd McConkey, Los Angeles Chargers at MIA
32. Keenan Allen, Los Angeles Chargers at MIA
33. Calvin Ridley, Tennessee Titans at LV
34. Wan’Dale Robinson, New York Giants vs. PHI
35. Chris Godwin, Tampa Bay Buccaneers vs. SF
36. Jameson Williams, Detroit Lions at KC
37. Ricky Pearsall, San Francisco 49ers at TB
38. Tre Tucker, Las Vegas Raiders vs. TEN
39. Cooper Kupp, Seattle Seahawks at JAX
40. D.J. Moore, Chicago Bears at WAS
41. Jerry Jeudy, Cleveland Browns at PIT
42. Khalil Shakir, Buffalo Bills at ATL
43. Travis Hunter, Jacksonville Jaguars vs. SEA
44. Rashid Shaheed, New Orleans Saints vs. NE
45. Romeo Doubs, Green Bay Packers vs. CIN
46. Keon Coleman, Buffalo Bills at ATL
47. Malik Washington, Miami Dolphins vs. LAC
48. Isaiah Bond, Cleveland Browns at PIT
49. Marquise Brown, Kansas City Chiefs vs. DET
50. Kendrick Bourne, San Francisco 49ers at TB
NFL: Jacksonville Jaguars defeat Kansas City Chiefs
Jacksonville Jaguars quarterback Trevor Lawrence celebrates after scoring a touchdown with under a minute remaining against the Kansas City Chiefs at EverBank Stadium in Jacksonville on October 6, 2025. Jacksonville defeated Kansas City 31-28. Photo by Joe Marino/UPI | License Photo
