1 of 6 | Philadelphia Eagles running back Saquon Barkley (26) slips past Los Angeles Rams defenders in the third quarter of NFL action Sunday at Lincoln Financial Field in Philadelphia. Photo by Laurence Kesterson/UPI | License Photo
Jonathan Taylor and Saquon Barkley lead my Top-50 fantasy football running back rankings for Week 4 of the 2025 season.
Christian McCaffrey, Derrick Henry and Bijan Robinson join Taylor and Barkley inside my Top 5. De’Von Achane, James Cook, Jordan Mason, Kyren Williams and Jahmyr Gibbs are my other Top-10 options.
Check out my Top-50 wide receiver rankings for Week 4 here. My top waiver-wire and free agent targets for Week 4 are available here.
All of my positional rankings will be updated until Week 4 kickoffs. Players also will be moved out of or adjusted within the rankings based on injuries.
Aaron Jones, James Conner, Najee Harris and Tyrone Tracy Jr., are among the injured running backs who should not be in fantasy football team starting lineups. Be sure to monitor your lineups for other developments.
Week 4 running back rankings
1. Jonathan Taylor, Indianapolis Colts at LAR
2. Saquon Barkley, Philadelphia Eagles at TB
3. Christian McCaffrey, San Francisco 49ers vs. JAX
4. Derrick Henry, Baltimore Ravens at KC
5. Bijan Robinson, Atlanta Falcons vs. WAS
6. De’Von Achane, Miami Dolphins vs. NYJ
7. James Cook, Buffalo Bills vs. NO
8. Jordan Mason, Minnesota Vikings vs. PIT
9. Kyren Williams, Los Angeles Rams vs. IND
10. Jahmyr Gibbs, Detroit Lions vs. CLE
11. Omarion Hampton, Los Angeles Chargers at NYG
12. Kenneth Walker III, Seattle Seahawks at ARI
13. Josh Jacobs, Green Bay Packers at DAL
14. Ashton Jeanty, Las Vegas Raiders vs. CHI
15. Trey Benson, Arizona Cardinals vs. SEA
16. Bucky Irving, Tampa Bay Buccaneers vs. PHI
17. J.K. Dobbins, Denver Broncos vs. CIN
18. Travis Etienne, Jacksonville Jaguars at SF
19. Breece Hall, New York Jets at MIA
20. Chuba Hubbard, Carolina Panthers at NE
21. Chase Brown, Cincinnati Bengals at DEN
22. Cam Skattebo, Los Angeles Rams vs. LAC
23. Alvin Kamara, New Orleans Saints at BUF
24. Javonte Williams, Dallas Cowboys vs. GB
25. Tony Pollard, Tennessee Titans at HOU
26. D’Andre Swift, Chicago Bears at LV
27. David Montgomery, Detroit Lions vs. CLE
28. Quinshon Judkins, Cleveland Browns at DET
29. Jaylen Warren, Pittsburgh Steelers vs. MIN
30. Rhamondre Stevenson, New England Patriots vs. CAR
31. Kareem Hunt, Kansas City Chiefs vs. BAL
32. Nick Chubb, Houston Texans vs. TEN
33. Bhayshul Tuten, Jacksonville Jaguars at SF
34. Jacory Croskey-Merritt, Washington Commanders at ATL
35. TreVeyon Henderson, New England Patriots vs. CAR
36. Ollie Gordon II, Miami Dolphins vs. NYJ
37. R.J. Harvey, Denver Broncos vs. CIN
38. Chris Rodriguez, Washington Commanders at ATL
39. Isiah Pacheco, Kansas City Chiefs vs. BAL
40. Brian Robinson Jr., San Francisco 49ers vs. JAX
41. Braelon Allen, New York Jets at MIA
42. Woody Marks, Houston Texans vs. TEN
43. Rachaad White, Tampa Bay Buccaneers vs. PHI
44. Rico Dowdle, Carolina Panthers at NE
45. Miles Sanders, Dallas Cowboys vs. GB
46. Tyler Allgeier, Atlanta Falcons vs. WAS
47. Kyle Monangai, Chicago Bears at LV
48. Justice Hill, Baltimore Ravens at KC
49. Blake Corum, Los Angeles Rams vs. IND
50. Kenneth Gainwell, Pittsburgh Steelers vs. MIN
NFL: Washington Commanders defeat Las Vegas Raiders
Washington Commanders wide receiver Luke McCaffrey (R) celebrates with quarterback Marcus Mariota (C) after scoring a touchdown during the fourth quarter against the Las Vegas Raiders at Northwest Stadium in Landover, Md., on September 21, 2025. The Commanders beat the Raiders 41-24. Photo by Bonnie Cash/UPI | License Photo
